Answer
Yes, it is possible to rent a home without a realtor: in Uruguay you can find an apartment without an intermediary. This approach requires more organization on your part.
Without an agent, the tenant checks the terms, handles correspondence, clarifies payments, arranges viewings, and keeps track of the documents. Do not transfer money solely because someone promises to hold an apartment: the property, recipient, and purpose of the payment should be clear.
A realtor can speed up viewings and communication, but their involvement does not replace reading the contract and inspecting the home. The choice between direct contact and an agent depends not on a simple "is it possible or not" rule, but on the specific property, the clarity of the transaction, the timing, and your willingness to manage it yourself before signing.